Domain Aliases

If I had a domain alias set up, could I redirect ie. do a 301 redirect in the web.config with something like this in the Application_BeginRequest event

string host = new Uri(Context.Request.Url.ToString()).Host;
if (host != 'www.site.com')
{
newURL = 'www.site.com';
Context.Response.Clear();
Context.Response.Status = '301 Moved Permanently';
Context.Response.AddHeader('Location', newUrl);
Context.Response.End();
}

Do you think there would be any issues with a domain alias?

thnks.